All definitions of 'genetic disease' and 'genetic susceptibility' require ceteris paribus clauses assuming necessary (though not sufficient) genetic and environmental background factors
Genetic susceptibility(being defined alongside genetic disease)
The tendency or increased likelihood that a person will develop a certain disease or condition because of their genes, even if they don't have it yet.
Necessary (though not sufficient)(describing what kind of factors are assumed in the definition)
Something that is 'necessary' means you absolutely need it for something to happen; 'not sufficient' means that having it alone isn't enough—you also need other things. Together, this means the genetic and environmental factors are required, but other factors matter too.
genetic disease(Criticized for abstracting disease away from organism-environment interactions.)
A reconceptualization of disease that relocates its locus from the organism and its physiological processes to the genome.
The logical interrelatedness of cause and effect—that is, whether a condition is necessary and/or sufficient for a given event to occur—is the approach taken to defining what makes a condition “genetic” in individuals. A strong sense of “genetic disease” is recognized when the genetic factor is both necessary and sufficient for the disease to arise “regardless of environment” (Wulff 1984), or when the genetic factor is sufficient for the disease to present “in all known environments” (Kitcher 19