Bernard Williams's notion of agent-regret shows that genuine moral residue after choice requires that something of independent value was sacrificed, which monism structurally cannot accommodate.

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Bernard Williams(as a defender of Humean philosophy): A late 20th-century British philosopher who wrote influential works on ethics, questioning whether morality can be truly objective and exploring the role of personal projects and desires in a good life.
Independent value(In this case, what gets sacrificed when making a moral choice): Something that matters or has worth in its own right, not just because it helps you achieve something else.
Structurally cannot accommodate(Describing why monism logically fails to account for moral residue): Built into the very framework of a theory in a way that makes it impossible for that theory to explain or allow for something—the theory's basic structure prevents it.
agent-regret(Williams argues that agent-regret is rational, contra utilitarianism which implies it is irrational when the agent acted optimally): A form of regret experienced by an agent specifically because of their causal role in bringing about a bad outcome, distinct from general regret that anyone might feel about an unfortunate event

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