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    Carmelics

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    LoyalLoyalJusticeJustice
    Made withinDC&Austin
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    Home/Original/inverse
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    Inverse View

    It is not the case that Huntington's disease qualifies as a genetic condition on both individual and population accounts

    ?Set your confidence on the premises below to see your aggregate.

    Reasons For

    2 perspectives
    Reason for 1 of 2
    ?
    • 1.Causation requires more than statistical correlation between mutation presence and symptom expression across a population.
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      Think about whether this reason is strong or weak

    • 2.Age of onset, symptom severity, and progression in HD vary substantially, suggesting gene expression is modulated by non-genetic factors.
      ?

      Think about whether this reason is strong or weak

    • 3.A condition whose phenotypic realization depends on developmental and environmental context is not adequately explained by genetic accounts alone.
      ?

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    Reason for 2 of 2
    ?
    • 1.Kendler and Crasnow argue that 'genetic condition' conflates distinct explanatory levels: molecular causation, population statistics, and clinical taxonomy.
      ?

      Think about whether this reason is strong or weak

    • 2.HD satisfies the individual account only under a ceteris paribus clause that smuggles in background conditions the genetic account cannot itself specify.
      ?

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    Reasons Against

    1 perspective
    Reason against
    ?
    • 1.A single mutant gene is necessary, and arguably sufficient given standard background conditions, for symptoms to appear in an individual
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      Think about whether this reason is strong or weak

    • 2.The presence and absence of disease symptoms across a population is accounted for by the presence and absence of the mutation
      ?

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