If non-additivity is the core obstacle, then mapping complete genotype-environment interaction surfaces via molecular methods transforms an unresolvable controversy into a tractable empirical research program.

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Genotype-environment interaction(in genetics and biology): The way your genes and your surroundings work together to shape who you are, where the effect depends on both factors influencing each other rather than acting separately.
Molecular methods(in scientific research): Scientific techniques that study and measure things at the level of molecules (tiny building blocks of matter) to understand how biological systems work.
Non-additivity(in genetics and research methodology): When two things working together create an effect that's different from just adding up their individual effects—like how mixing two colors doesn't simply combine their individual properties.
Tractable empirical research program(in research methodology and philosophy of science): A scientific study plan that is actually solvable and testable through real-world observation and experimentation, rather than just theoretical.

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