If our spatial and causal representations systematically enable successful prediction and intervention in the world, inference to their mind-independent reality is more parsimonious than positing an unknowable thing-in-itself.

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Mind-independent reality(what preserves a role in classification despite scheme-dependence): The idea that the world exists and has certain features whether or not any person is thinking about it or aware of it.
Parsimonious(as used in philosophy of science and logic): Simple and avoiding unnecessary complexity; preferring the explanation that requires the fewest assumptions or extra moving parts.
Spatial and causal representations(as used in epistemology and metaphysics): The mental pictures and descriptions we use to understand how things are arranged in space and how one thing causes another to happen.
inference(Nyāya epistemology): A component of epistemology in Nyāya philosophy; a veritable inference yields knowledge about the world and must have premises that are themselves known
thing-in-itself(Kant's distinction between appearances and things-in-themselves in the Second Antinomy): An entity whose properties and divisions subsist independently of any act of experience or cognition, such that its decomposition into parts would form a completed (or completable) sequence.

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