John Stuart Mill observed in 'Three Essays on Religion' that nature's indifference to suffering is a positive mark against a benevolent omnipotent designer, not merely an absence of confirming evidence.

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Absence of confirming evidence(contrasting with positive evidence against benevolent design): The lack of proof or signs that would support a claim; here, the difference between having no evidence for something versus having evidence against it.
Designer (in theological sense)(referring to god or a creator figure): A creator or intelligent being responsible for designing and creating the universe; often refers to God in philosophy of religion.
John Stuart Mill(one side of the debate): An influential 19th-century British philosopher who argued that scientific knowledge comes from careful observation and gathering evidence from the world.
Three Essays on Religion(as a historical reference): A collection of essays by Mill published after his death that explores questions about God's nature and the problem of evil in the world.

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