Quine's argument in 'Two Dogmas of Empiricism' establishes that any statement can be held true come what may if sufficiently radical adjustments are made elsewhere in the theoretical web.

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Hold true come what may(describing how we can protect beliefs from being proven wrong): To refuse to accept that something is false, no matter what evidence or contradictions appear.
Quine(as a proper name referring to the philosopher whose theory is being discussed): Willard Van Orman Quine was a 20th-century American philosopher who wrote about how we know things and how language works. In this statement, we're discussing one of his specific ideas about observation.
Theoretical web(the metaphor used to explain how knowledge is organized): An image Quine uses to describe how all our beliefs and knowledge are interconnected like a spider web, where each belief is supported by and connected to all the others.
Two Dogmas of Empiricism(as the title of the work being referenced): A famous 1951 essay by Quine arguing against two widely-accepted beliefs about meaning and knowledge that philosophers had taken for granted.

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