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    The fundamental concept of a gene, across research contex... — Carmelics
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    Home/Philosophy of Language
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    The fundamental concept of a gene, across research contexts, is a stretch of DNA whose linear sequence provides a template for a gene product (mRNA transcript or polypeptide).

    Philosophy of LanguageProof of definition segments
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    1 reason for
    2 reasons against

    Reasons For

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    Reason for
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    • 1.Specific research contexts determine whether genes are considered to include introns, exons, regulatory regions, or promoter regions.
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    • 2.Despite contextual variation, a common template-providing function remains consistent across these contexts.
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    Reasons Against

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    • 1.Kitcher and Griffiths argue that 'gene' picks out multiply realized functional roles rather than any single structural or mechanistic property of DNA.
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    • 2.If the gene concept is irreducibly pluralistic across research contexts, as Moss and Waters independently argue, then no single template-function definition can be fundamental.
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    • 3.The claim's appeal to contextual variation in P1 implicitly concedes pluralism, making P2's assertion of a common function an unsupported unifying move.
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    Reason against 2 of 2
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    • 1.RNA genes (tRNA, rRNA, miRNA) produce functional products without any polypeptide stage, yet are uncontroversially classified as genes.
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    • 2.A definition requiring a 'template for mRNA or polypeptide' excludes paradigm cases, violating the extensional adequacy criterion for successful definitions.
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    Philosophy of LanguageProof of definition segments

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    Related

    A definition requiring a 'template for mRNA or polypeptide' excludes paradigm ca...Despite contextual variation, a common template-providing function remains consi...If the gene concept is irreducibly pluralistic across research contexts, as Moss...Kitcher and Griffiths argue that 'gene' picks out multiply realized functional r...
    +3 moreShow less
    RNA genes (tRNA, rRNA, miRNA) produce functional products without any polypeptid...Specific research contexts determine whether genes are considered to include int...The claim's appeal to contextual variation in P1 implicitly concedes pluralism, ...

    Similar

    The classical molecular gene concept defines a gene as a stretch of DN...88%No single theoretical definition of 'gene' captures all the ways the t...83%The gene concept lacks a theoretical core and should be defined pragma...83%Pluralism about the gene concept is the appropriate position, given th...82%

    Source

    AI-extracted1/3 agreementValid
    SEP: human-genome
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    Recent philosophical efforts to define genes have sought to capture these practices. C. Kenneth Waters (1994) recognizes that specific research contexts determine whether genes are considered to include introns as well as exons, or regulatory or promoter regions as well as open reading frames (ORFs), but argues that what remains “fundamental” across these contexts is the concept of a gene as a stretch of DNA the linear sequence of which provides a template for a gene product, whether mRNA transc
    Extraction notes

    Validity: Extracted via Max plan + API grounding/validity checks

    Details

    Type
    claim
    Perspectives
    3 (1 for, 2 against)
    Edits
    1 edit