Therefore the variant proposition is not uniquely determined by the replacement sequence alone, but depends on holistic semantic relations Bolzano's substitution procedure leaves unspecified.

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Bolzano: Bolzano refers to Bernhard Bolzano (1781–1848), an Austrian mathematician and philosopher who made important discoveries about how functions behave and how infinity works in mathematics. Though his work wasn't widely recognized during his lifetime, he's now considered a pioneer who helped lay the groundwork for modern calculus and logic. His most famous contribution is the Bolzano-Weierstrass theorem, a fundamental principle in mathematics that helps us understand continuous functions and infinite sequences.
Bolzano's substitution procedure(as used in logic and semantics): A logical method Bolzano created for understanding what happens to a statement's meaning when you replace certain words with other words—but it has limitations in capturing all the connections between concepts.
Holistic semantic relations(as used in philosophy of language): The way that the meaning of words depends on the whole context and how they connect to everything around them, not just on isolated definitions.
Replacement sequence(as used in logic)

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