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    LoyalLoyalJusticeJustice
    Made withinDC&Austin
    Statements
    321,452
    Perspectives
    108,905
    Topics
    42
    Home/Original/inverse
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    Inverse View

    It is not the case that Enrolling a research candidate in a trial remains legitimate even when the candidate fails to comprehend disclosed information despite repeated efforts.

    ?Set your confidence on the premises below to see your aggregate.

    Reasons For

    2 perspectives
    Reason for 1 of 2
    ?
    • 1.Valid consent requires actual understanding, not merely the opportunity for understanding, as Faden and Beauchamp argue in 'A History and Theory of Informed Consent' (1986).
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    • 2.Enrollment without comprehension treats the candidate as a means to research ends, violating Kantian respect for persons as rational autonomous agents.
      ?

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    • 3.Procedural compliance with disclosure cannot substitute for the substantive condition of competent understanding that grounds the moral legitimacy of consent itself.
      ?

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    Reason for 2 of 2
    ?
    • 1.Paul Appelbaum's competency standard requires that candidates demonstrably manipulate disclosed information to reach a reasoned decision, not merely receive it.
      ?

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    • 2.When comprehension fails despite repeated efforts, investigators have epistemic evidence that the candidate lacks decision-making capacity, triggering surrogate consent obligations rather than enrollment authorization.
      ?

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    Reasons Against

    1 perspective
    Reason against
    ?
    • 1.Investigators fulfill their obligations by giving candidates the opportunity to issue autonomous authorization.
      ?

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    • 2.Investigators avoid potential fraud by providing disclosure.
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    • 3.Investigators treat candidates fairly by offering the opportunity for informed consent.
      ?

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