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    Technological fixes for disease are directed at the genom... — Carmelics
    Home/Bioethics
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    Technological fixes for disease are directed at the genome rather than at the organism.

    Bioethics
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    1 reason for
    2 reasons against

    Reasons For

    1 perspective
    Reason for
    ?
    • 1.The beanbag conception of the organism treats organisms as reducible to collections of genes.
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    • 2.The concept of genetic disease relocates the locus of disease from the organism to the genome.
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    • 3.When disease is located in the genome, interventions target the genome.
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    Reasons Against

    2 perspectives
    Reason against 1 of 2
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    • 1.Gene therapy and CRISPR interventions act on somatic or germline cells as embodied biological systems, not on abstract genomic information alone.
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    • 2.The distinction between targeting 'the genome' and 'the organism' collapses when genomic interventions necessarily occur within and through the physiological context of a living body.
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    • 3.Moss and Keller's developmental systems theory shows that gene expression is inseparable from cellular and organismal environment, making 'genome-directed' therapy a category error.
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    Reason against 2 of 2
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    • 1.The beanbag conception attributed to classical population genetics was explicitly rejected by Ernst Mayr and has not governed molecular medicine's actual practice.
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    • 2.Contemporary precision medicine explicitly integrates genomic, proteomic, environmental, and phenotypic data, targeting disease at multiple levels of biological organization simultaneously.
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    Topics

    Bioethics

    Connections

    1 topic

    Consciousness & Mind2 linked

    Related

    Contemporary precision medicine explicitly integrates genomic, proteomic, enviro...Gene therapy and CRISPR interventions act on somatic or germline cells as embodi...Moss and Keller's developmental systems theory shows that gene expression is ins...The beanbag conception attributed to classical population genetics was explicitl...
    +4 moreShow less
    The beanbag conception of the organism treats organisms as reducible to collecti...The concept of genetic disease relocates the locus of disease from the organism ...The distinction between targeting 'the genome' and 'the organism' collapses when...When disease is located in the genome, interventions target the genome.

    Similar

    When disease is located in the genome, interventions target the genome...87%The concept of genetic disease relocates the locus of disease from the...83%Molecular genetics reduces organisms to their genomes.78%Genetic reductionism directs technological fixes at the genome, includ...76%

    Source

    AI-extracted1/3 agreementValid
    SEP: human-genome
    View source passageHide passage
    Besides these attempts to reduce species to beanbags of genes, genetic reductionism enters in attempts to explain cellular or organismal properties solely in terms of genes, or entire organisms in terms of genomes. Gilbert (1992) endorses an essentialism of this sort as well: “The information carried on the DNA, that genetic information passed down from our parents,” he writes, “is the most fundamental property of the body” (p. 83), so much so, in fact, that “one will be able to pull a CD out of
    Extraction notes

    Validity: Extracted via Max plan + API grounding/validity checks

    Details

    Type
    claim
    Perspectives
    3 (1 for, 2 against)
    Edits
    1 edit